DL-Panthenol, aka Pro-Vitamin B5, is a stable racemic mixture of D-Panthenol and L-Panthenol. The human body readily absorbs DL-Panthenol through the skin and it rapidly converts D-Panthenol to Pantothenic Acid (Vitamin B5), a natural constituent of healthy hair and a substance present in all living cells. When it comes to moisturization properties- improved hydration, reducing water loss and maintaining skin elasticity and softness- this racemic mixture is 100% active. When applied for skin epithelization (wound healing), only D-Panthenol is converted to Vitamin B5 and not the L-Panthenol, so D,L-Panthenol has only half of the physiological activity of D-Panthenol.
Studies have shown D-Panthenol promotes stimulation of epithelization, granulation, mitigation of itching and has an anti-inflammatory effect. When used in formulations over the course of three to four weeks, it has the potential to improve the appearance of the skin, including dryness, roughness, scaling, pruritus and erythema.
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